Click chemistry has led to remarkable effects of self-modifying antibiotics on bacterial resistance. Photo: File
New York: Antibiotics are turning themselves into ineffective drugs in the face of disease worldwide. Now, with new types of antibiotics, this serious problem that we call ‘antibiotic resistance’ can be eliminated.
According to the World Health Organization, tens of millions of people around the world are dying from the ineffectiveness of antibiotics. This is why it has been included in the top 10 threats to global health.
The reason is that when the same type of antibiotic is used on bacteria, viruses and germs, the germs change themselves and the drugs become ineffective.
Now Cold Spring Harbor Laboratory (CSHL) professor John Moses and his colleagues have created a new antibiotic thanks to ‘click chemistry’, which will win the 2022 Nobel Prize. The atoms of which are constantly changing themselves in a changing context.
Professor John saw a molecule called ‘bull valine’ discovered a year ago, whose atoms can change their position.
‘Bill Villain’ can take on millions of possible forms. Now Dr. John added an antibiotic called Vancomycin to it. And so a new antibiotic came out and tested it on moth larvae called Vax, which is also a common method.
After this drug was used several times, it was found that the bacteria did not show any resistance and thus the efficacy of click chemistry was revealed. Experts have called it a wonderful development.
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