Osaka: Japanese scientists eSuch A drug has been developed that can regrow human teeth.
Katsu Takahashi, from Kitano Hospital and Kyoto University in Osaka, Japan, said scientists wanted to do something to help people who had or had lost teeth.
The breakthrough comes after years of examining an antibody called Uterine Sensitization-Associated Gene-1 (USAG-1), which was shown to inhibit tooth development in mice and ferrets.
In 2021, scientists from Kyoto discovered a monoclonal antibody that interferes with USAG-1 binding between molecules called bone morphogenetic protein (BMP).
“Scientists knew that suppressing USAG-1 was beneficial for tooth development,” study co-author Katsu Takahashi said in a press release. However, it was not known whether doing so would be sufficient.
Ferrets are die-five-toothed animals and have the same dental arrangement as humans. Scientists now have to see to what extent this similarity is as the trial will begin on humans from September this year.
The study, which will last for 11 months, will be conducted on 30 men between the ages of 30 and 64, who will be missing at least one tooth.
It should be noted that no adverse effects of the medicine have been revealed in the research done on animals.
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